TEACHING ACTIVITY COMMITTEE FOR Ph.D. COURSE
Prof. Elisa Greggio
Prof. Andrea Pilastro
Prof. Natascia Tiso
Prof. Michela Zottini
ORGANIZATION OF THE TEACHING ACTIVITY
1) Obligatory attendance of 10 seminars/year. Signature of speaker or college member is required.
2) Obligatory attendance of 3 courses in 3 years.
3) Obligatory attendance of 1 course/years paid by the Department of Excellence Project.
4) The seminars will be held ALWAYS on Thursday of the week, preferentially starting at 14.00.
TEACHING ACTIVITY 2021
1. Science Communication, Fundraising & Career Development (18 hours) – via ZOOM.
Dates: 3, 4, 5, 17, 18 February - 3 March, 9.30 a.m.
15, 16 February – 1, 2, 8 March, 14.00 p.m.
Speakers: Ralf Dahm, Institute of Molecular Biology (IMB), Germany – Natascia Tiso, DeBio, UniPd
To be successful, scientists need to raise funding for their projects and effectively communicate their science. No career can be built without writing successful grant applications or publishing high-impact papers, presenting attractive posters and giving compelling talks. It is therefore essential that scientists learn early on in their careers how best to present their data and ideas in different contexts.
2. Deadly sins of scientific research (8 hours) – via ZOOM.
Dates: 4, 11, 18, 25 February, 14.00 p.m.
Speaker: Lucio Bonato, DeBio, UniPd
By means of open discussions and exercises on fictional and real cases, PhD students will be made aware of the most frequent faults in scientific practice, including flaws in planning research and in interpreting results, logical and statistical fallacies, and inappropriate behavior in scientific publication. As a result, they will be helped in strengthening accuracy, integrity and effective scientific work.
3. Experimental design and Interpretation of mitochondrial function assays (16 hours) – via ZOOM.
Dates: 8, 9, 10, 12, 22, 23, 24, 26 February, 15.00 p.m.
Speaker: Maria Eugenia Soriano, DeBio, UniPd
This course will explain the bases for the experimental design of mitochondrial functional assays. For each section, the choice of the different buffers, the relevance of their composition, and the procedures will be discussed. This knowledge will be applied to the design of a hypothetic experiment. To conclude, we will analyze and interpret the possible results. The course aims to provide the conceptual tools, from the physiological and biochemical knowledge, to design novel and useful experiments to characterize specific mitochondrial aspects.
4. Science Communication in Biomedicine and Biosciences. How to communicate the impact of scientific projects to different audiences (15 hours) – via ZOOM.
Dates: 3, 12, 17, 24, 31 March – 7, 14, 21, 28 April - 7 May, 16.00 p.m.
Speaker: Elisabetta Mutto-Accordi, Communications consultant and a freelance journalist.
The learning program focuses on simulations and exercises in the classroom and on direct involvement of participants. On this base, PhD students will practice changing their communicative approach using also diverse range of media. They will develop basic skills to convey the content of their work at a level that a general audience can understand.
5. Microscopy, Imaging and Computational Image Processing (14 hours).
Dates: 10, 15, 22, 29 March – 7, 14, 21 April, 14.30 p.m.
Speakers: Marta Giacomello, DeBio, UniPd – Francesco Argenton, DeBio, UniPd
Basic Principles of microscopy; Fluorescence and Confocal Microscopy; Fluorescent Probes (for fixed and live samples); Advanced techniques in fluorescence microscopy; ImageJ.
6. Ecological modelling basics (16 hours).
Dates: 30, 31 March – 13, 14, 20, 21, 27, 30 April 2021, 15.30 p.m.
Speaker: Alberto Barausse, DeBio, UniPd
Introduction to ecological modelling: models and holism. The different steps of the procedure to construct an ecological model. Balance, transport and chemical reaction models, ecotoxicological models. Settling and resuspension; Energetic factors. Light extinction. Photosynthesis and primary production. Algal growth. Light and nutrient limitation. Grazing. Nitrogen and Phosphorus cycle, wetlands and water quality management. Metabolic - Fish growth models The focus on these different topics will be tailored according to the background of the students and their specific PhD.
7. Advanced Biochemical Methods (8 hours) – Room G, mezzanine floor, Polo Vallisneri.
Dates: 1, 3, 16, 17 June 2021, 16.30 p.m.
Speakers: Luigi Leanza, DeBio, UniPd – Laura Cendron, DeBio, UniPd
The course will describe the more advanced and used biochemical methodologies: Principle of Mass Spectrometry and application to biological problems; New tools in the study of protein-protein interaction; Gene editing by CRISPR/Cas9 and its updated variants; High-throughput analysis.
8. Invertebrate physiology: from development to immunity (10 hours) – via ZOOM.
Speakers: L. Ballarin, M. Brivio, C. de Pittà, F. Sandrelli, P. Venier
24 May, 14.30 - 15.15 p.m., Federica Sandrelli (DeBio, UniPd): Innate immune response and antimicrobial peptides in the silkworm Bombyx mori.
25 May, 14.30 - 15.15 p.m., Loriano Ballarin (DeBio, UniPd): The innate immune responses of colonial ascidians.
25 May, 16.00 - 16.45 p.m., Maurizio Brivio (Department of Theoretical and Applied Sciences, Uninsubria): When Appearance Misleads: Role of the Entomopathogens Surface in the Relationship with their Hosts.
26 May, 14.30 - 15.15 p.m., Paola Venier (DeBio, UniPd): What to learn from the immune responses of marine bivalves?
26 May, 16.00 – 16.45 p.m., Cristiano de Pittà (DeBio, UniPd): Can the transcriptome approach reveal the ontogenesis of Antarctic krill?
9. Humans in a dish: the potential of organoids in modeling diseases (12 hours) – via ZOOM.
Speakers: M. Bellin, V. Corbo, B. Frossi, M. Mognato, M. Trevisan, T. Zelante
7 June, 14.30-15.15 p.m., Maddalena Mognato (DeBio, UniPd): Organoids as a 3D-model to study the DNA-damage response pathway.
7 June, 16.00-16.45 p.m., Teresa Zelante (Department of Experimental Medicine, Pathology section, DEM, UniPg): Breakdown of symbiosis in radiation-induced oral mucositis: how tongue organoids may help.
8 June, 14.30-15.15 p.m., Barbara Frossi (Department of Medical Area, DAME, UniUd): Crosstalk between immune and epithelial cells in intestinal organoid development.
8 June, 16.00-16.45 p.m., Vincenzo Corbo (Department of diagnostic and public health Ddsp, UniVr) : Organoids to study the biology of pancreatic cancer.
9 June, 14.30-15.15 p.m., Marta Trevisan (DMM, UniPd): Brain organoids: a new platform to study the pathogenesis of neurotropic viruses.
9 June, 16.00-16.45 p.m., Milena Bellin (DeBio, UniPd): Multicell-type cardiac microtissues from human stem cells: modelling inherited and acquired diseases, from arrhythmia to cardiotoxicity.
10. Essential and dispensable genes in living organism (4 hours) – via ZOOM.
Dates: 14, 15 June
Speaker: Paola Venier, DeBio, UniPd
The course will focus on genetic and evolutionary aspects of genome size and gene content, encompassing the following topics: 1) Genome size, architecture and evolutionary trends in viruses, prokaryotes and eukaryotes; 2) Microbial pan-genomes, how do they work? 3) Evidence for essential and dispensable genes in plants and animals. 4) The Mytilus dispensable gene fraction: practical implications for gene expression studies.
11. Basic Statistics for biological data (8 hours) – via ZOOM
Dates: 5, 6, 7, 8 July 2021, 14.30 p.m.
Speaker: Rimantas Eidukevicius, Vilnius University, Lithuania.
- Introduction to descriptive statistics and plots.
- Parametric Statistical inference: two groups comparison
- Non-Parametric Statistical inference: two groups comparison
- Inference for multi-groups comparisons
Practical session with R software
12. Gene Therapy for Human Diseases (4 hours) – Room B, ground floor, Polo Vallisneri.
Dates: 12, 19 July 2021, 14.30 p.m.
Speaker: Libero Vitiello, DeBio, UniPd
A not-so-obvious definition of Gene Therapy and a summary of its history.
Types of vectors used in gene therapy, viral and synthetic, and their respective strengths and weaknesses.
Something old, something new: established and innovative therapeutic strategies.
Where are we now in clinical application? Examples of approved and experimental gene therapies in human patients.
Where to from here? Foreseeable developments of gene therapy with the arrival of genome editing.
In-depth discussion of few landmark papers, chosen also based on the feedback of the students on day one.
Courses to organize:
1. Fellowship/grant proposal writing ( 8 hours).
Speakers: Ildi Szabò , DeBio, UniPd - Luca Scorrano, DeBio, UniPd
The course offers the theoretical framework and practical advice on how to successfully write a post-doctoral fellowship application for a competitive international grant program (such as EMBO, Marie-Curie, Human Frontiers, and so on).
2. Cannabis and nicotine - plant secondary metabolites and how they function in plants and humans (4 hours). Course offered by the Department of Excellence program.
Speaker: U. Vothknecht, University of Bonn, Germany.